GSK2334470 - CAS# 1227911-45-6 one (dimaleate) or 400 mg/kg
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GSK2334470 - CAS# 1227911-45-6 one (dimaleate) or 400 mg/kgGSK2334470 is a potent 3 phosphoinositide dependent protein kinase (PDK1) inhibitor (IC50 ~ 10 nM), which does not suppress the activity of 93 other protein kinases including 13 AGC kinases most related to PDK1 at 500 fold higher concentrations. GSK2334470 also inhibited T loop phosphorylation and activation of Akt. GSK2334470 will be a useful tool for delineating the roles of PDK1 in biological processes. Product information CAS Number: 1227911 45 6
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