SR-59230A oxalate - CAS# 174689-39-5 60022 183322-45-4

183322-45-4

Formula: C14H14ClN3O2S

Combined inhibition of EGFR and CK2 augments the attenuation of PI3K-Akt-mTOR signaling and the killing of cancer cells

CX-6258 exhibited in vitro synergy with chemotherapeutics and robust in vivo efficacy in two Pim kinases driven tumor models

SR-59230A oxalate - CAS# 174689-39-5 60022 183322-45-4SR 59230A oxalate, CAS No. 174689 39 5, is a potent and selective 3 adrenoceptor antagonist (IC50 values are 40, 408 and 648 nM for 3, 1 and 2 receptors respectively). SR 59230A was subsequently shown to also act at 1 adrenoceptors at high doses. It has been shown to block the hyperthermia produced by MDMA in animal studies. SR 59230A blocks MDMA induced hyperthermia, while at high concentrations it blocks hyperthermia but also increases heat loss