Pomalidomide 4-PEG1-amine - CAS# 2154342-56-8 050 Enhanced optineurin E50K-TBK1 interaction evokes

Enhanced optineurin E50K-TBK1 interaction evokes protein insolubility and initiates familial primary open-angle glaucoma

The first class (DuP-753 sensitive) represents approximately 85% of the total binding sites for AII and possesses a high affinity (IC50 of 92

doi: 1158/1535-7163

VU 0458298-2

Pomalidomide 4-PEG1-amine - CAS# 2154342-56-8 050 Enhanced optineurin E50K-TBK1 interaction evokesPomalidomide 4 PEG1 amine, CAS No. 2154342 56 8, cereblon ligand with PEG linker and terminal amine for onward chemistry. Functionalized cereblon ligand for PROTAC research and development; incorporates an E3 ligase ligand plus a PEG1 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. Product information CAS Number: 2154342 56 8 Molecular Weight: 396. 83