MEF-2 Polyclonal Antibody, 50ul[BT-AP05322] Antibody Development Alternative splicing of this gene

Alternative splicing of this gene results in two transcript variants| which contain alternative first exons that are spliced to the remaining common exons

Members of this family have been identified in plants| vertebrates| and invertebrates| and they share a conserved N-terminal transcription activation region and a conserved C-terminal DNA and phosphatidylinositol-phosphate binding region

A polymorphism in an intron of this gene may be associated with longevity

This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL)

MEF-2 Polyclonal Antibody, 50ul[BT-AP05322] Antibody Development Alternative splicing of this geneThe protein encoded by MEF2A is a DNA binding transcription factor that activates many muscle specific, growth factor induced, and stress induced genes. The encoded protein can act as a homodimer or as a heterodimer and is involved in several cellular processes, including muscle development, neuronal differentiation, cell growth control, and apoptosis. Defects in this gene could be a cause of autosomal dominant coronary artery disease 1 with