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Necrostatin-1 faxine Hydrochloride ClH/c1-18(2)13-16(17(19)11-5-4-6-12-17)14-7-9-15(20-3)10-8-14

Necrostatin-1 faxine Hydrochloride ClH/c1-18(2)13-16(17(19)11-5-4-6-12-17)14-7-9-15(20-3)10-8-14

Name: Necrostatin-1 faxine Hydrochloride ClH/c1-18(2)13-16(17(19)11-5-4-6-12-17)14-7-9-15(20-3)10-8-14
Brand: finou-maps.com
SKU: 59570538340
Price: 80.00 USD
Availability: InStock
Rating: 4.36 (21 reviews)

SKU: 59570538340

4.4

PLN80.00 PLN115.00

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Necrostatin-1 faxine Hydrochloride ClH/c1-18(2)13-16(17(19)11-5-4-6-12-17)14-7-9-15(20-3)10-8-14Necrostatin 1 is a potent and selective inhibitor of necroptosis, a mechanism of programmed cell death separate from apoptosis. Necrostatin 1 functions as an allosteric inhibitor of the death domain receptor associated adaptor kinase RIP (RIP1) in the necroptosis pathway. While affecting this distinct cell death pathway, Necrostatin 1 does not present any perturbation of the Fas TNFR triggered canonical apoptosis cascade. Necrostatin 1 inhibits RIP1

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Description

ClH/c1-18(2)13-16(17(19)11-5-4-6-12-17)14-7-9-15(20-3)10-8-14

HMN-214 is an oral prodrug of HMN-176

benzenesulfonic acid

Chemical Name: 4-Chloro-1-(4-piperidyl)-N-[5-(2-pyridyl)-1H-pyrazol-4-yl]pyrazole-3-carboxamide Hydrochloride

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