AES Polyclonal Antibody, 50ul Buffer Solutions Defects in ATG16L1 are a

Defects in ATG16L1 are a cause of susceptibility to inflammatory bowel disease type 10 (IBD10)

This gene encodes a member of the CHIC family of proteins

including heparan sulfate

LOST1 or IFITMD3 (interferon-induced transmembrane domain-containing protein D3)

AES Polyclonal Antibody, 50ul Buffer Solutions Defects in ATG16L1 are aThe protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho a protein involved in neurogenesis during embryonic development. The encoded protein which belongs to the groucho TLE family of proteins can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms