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A-674563 - CAS# 552325-73-2 Size:Solid 2 mg with VLX1570 is lethal to

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A-674563 - CAS# 552325-73-2 Size:Solid 2 mg with VLX1570 is lethal toA 674563 is a potent, orally available Akt1 inhibitor with an IC50 value of 11nM. Also displays activity against PKA and CDK2 with IC50 values of 16nM and 46nM respectively. Product information CAS Number: 552325 73 2 Molecular Weight: 358. 44 Formula: C22H22N4O Synonym: A 674563 A674563 Chemical Name: (2S) 1 {[5 (3 methyl 2H indazol 5 yl)pyridin 3 yl]oxy} 3 phenylpropan 2 amine Smiles: CC1NN=C2C=CC(=CC2=1)C1=CN=CC(=C1)OC[C@@H](N)CC1C=CC=CC=1

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Description

with VLX1570 is lethal to ibrutinib- or bortezomib-resistant Waldenstrom macroglobulinemia tumor cells

InChi: InChI=1S/C14H8FNO3S/c15-9-3-1-8(2-4-9)11-6-5-10(19-11)7-12-13(17)16-14(18)20-12/h1-7H

It inhibits an enzyme needed for the growth of T cells and B cells

InChi: InChI=1S/C6H12F2N2O2

A-674563 - CAS# 552325-73-2 Size:Solid 2 mg with VLX1570 is lethal toA 674563 is a potent, orally available Akt1 inhibitor with an IC50 value of 11nM. Also displays activity against PKA and CDK2 with IC50 values of 16nM and 46nM respectively. Product information CAS Number: 552325 73 2 Molecular Weight: 358. 44 Formula: C22H22N4O Synonym: A 674563 A674563 Chemical Name: (2S) 1 {[5 (3 methyl 2H indazol 5 yl)pyridin 3 yl]oxy} 3 phenylpropan 2 amine Smiles: CC1NN=C2C=CC(=CC2=1)C1=CN=CC(=C1)OC[C@@H](N)CC1C=CC=CC=1

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