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Research indicates that FOXO factors may have both protective and detrimental effects in the context of neurodegeneration, depending on how they are regulated

Inhibitors of HIF-PHD can promote endogenous erythropoietin (EPO) by stabilizing and activating HIF and erythropoiesis (Joharapurkar et al., 2018)

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A 2015 study by Huang and colleagues in Drug Design, Development and Therapy used a rat alkali-burn model (n=10 per group) and HUVECs treated with BPC-157 at 200800 ng/mL, reporting accelerated wound closure with enhanced granulation tissue, reepithelialization, and dermal remodeling by day 18, alongside increased endothelial migration and vascular tube formation in vitro via ERK1/2 phosphorylation though the abstract does not report numeric % wound closure or p-values