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The elimination half-life is approximately 2 hours, which is relatively short compared to non-peptide GH secretagogues like MK-677 (half-life approximately 5 hours)

Inflammopharmacology 29 (2), 549559

113,123 EPO also down-regulates the ability of renal tissue to produce increased levels of intercellular adhesion molecule 1 and proinflammatory cytokines and chemokines in response to ischemia