TPCA-1 - CAS# 507475-17-4 olet InChi: InChI=1S/C21H24N2O2/c1-13(2)22-9-10-23-20-7-5-16(14(3)24)11-18(20)19-12-17(15(4)25)6-8-21(19)23/h5-8
Pay in 4 interest-free payments of $25.93 Learn more
Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Aug 2 - Aug 7
Live Spec
TPCA-1 - CAS# 507475-17-4 olet InChi: InChI=1S/C21H24N2O2/c1-13(2)22-9-10-23-20-7-5-16(14(3)24)11-18(20)19-12-17(15(4)25)6-8-21(19)23/h5-8TPCA 1 is a potent IKK 2 inhibitor. TPCA 1 is also an effective inhibitor of STAT3 phosphorylation, DNA binding, and transactivation in vivo. It selectively repressed proliferation of NSCLC cells with constitutive STAT3 activation. TPCA 1 as a direct dual inhibitor for both IKKs and STAT3, whereas treatment targeting EGFR only could not sufficiently repress NF B and STAT3 pathways for lung cancers harboring mutant EGFR. Therefore, synergistic
Store: finou-maps.com · Domain: finou-maps.com
