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doi: 10.1016/s1566-0702(00)00176-4 66

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To find out a specific mechanism, a comparison with the becaplermin (recombinant human plateletderived growth factor homodimer of B chains, PDGF-BB) was the focus of the two additional studies using excisional wounds in diabetic rats and mice (Figure 2) (Seveljevic-Jaran et al., 2006

This review from Shanghai University of Traditional Chinese Medicine highlights how the #NLRP3 #inflammasome links #MetabolicStress to inflammation, oxidative stress, #pyroptosis, and #fibrosis in #DiabeticCardiomyopathy, and evaluates emerging strategies targeting NLRP3 signaling to break the metabolisminflammation cycle and enable sustained therapeutic remission