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In rat coronary artery smooth muscle cells, treatment with liraglutide inhibited VSMC phenotypic transition induced by advanced glycation end products (AGEs), through blocking the nuclear factor-B (NF-B) signaling pathway and activating the protein kinase A (PKA) signaling pathway

Collectively, these results demonstrate that GLP-1RA not only improves basal glycemic control and reduces food intake in db/db mice but also promotes lipid utilization without altering overall energy expenditure

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If youre experiencing any adverse reactions or concerns, make sure to reach out to your healthcare provider for help